Rachel S. Hianik1, Mehmet A. Bilen1,2, Ragini R. Kudchadkar1,2, Margie D. Dixon1, Melinda L. Yushak1,2, Rebecca D. Pentz1,2*
1Winship Cancer Institute, USA
2Emory University School of Medicine, USA
BACKGROUND: Immunotherapy is continually being integrated into cancer care, but there is no research on communication strategies to explain it. We examine how metaphors are being used in clinical oncology to describe immunotherapy to patients.
METHODS: We observed and audio-recorded 33 first-time conversations about immunotherapy. We took note of each metaphor used in each conversation and conducted a follow-up interview to assess patient understanding of the metaphor used.
RESULTS: Metaphors were used and understanding was assessed 43 times in the 33 conversations about immunotherapy. We describe 14 metaphors used to describe four immunotherapy topics. Patients understood the metaphors 54% of the time.
CONCLUSION: Metaphors are being used by providers as a way to describe immunotherapy in clinical oncology. We hope that the examples we provide can be adapted and expanded by other oncologists to assist them in communication with patients about immunotherapy.DOI: 10.29245/2690-0009/2019/3.1108 View / Download Pdf
Typhaine Grenet1,2, Caroline Kannengiesser3,4,5, Raphael Borie3, 5, 6, 7, Audrey Giocanti-Aurégan2
1Centre d’imagerie et de Laser, 11 rue Antoine Bourdelle, Paris, France
2Ophthalmology department, Avicenne hospital, Paris 13 University, APHP, Bobigny, France
3Université Paris Diderot, Paris, France
4Laboratoire de Génétique, APHP, Hôpital Bichat, Paris, France
5Service de Pneumologie A, Centre de Compétence des Maladies Pulmonaires Rares, Paris, France
6DHU FIRE, Hôpital Bichat, APHP, Paris, France
7INSERM, Unité 1152, Paris, France
Purpose: To report a case of bilateral Coats Plus syndrome associated with a TERT gene deletion.
Case report: A 35-year-old man with a history of liver transplant, hematological impairment, and lung fibrosis due to a TERT gene mutation was referred for blurred vision in the right eye (RE). Ophthalmological examination revealed bilateral peripheral ischemia of the retina associated with bilateral peripheral telangiectasia and telangiectasia at the posterior pole of the RE responsible for macular edema, confirmed by multimodal imaging.
Conclusion: In this young patient with bilateral Coats-like lesions associated with systemic liver and lung failures due to a TERT mutation, we report a case of Coats plus syndrome due to a TERT mutation.DOI: 10.29245/2690-0009/2019/3.1107 View / Download Pdf